A photothermal and self-induced Fenton dual-modal antibacterial platform for synergistic enhanced bacterial elimination

NWIPB OpenIR

	A photothermal and self-induced Fenton dual-modal antibacterial platform for synergistic enhanced bacterial elimination
	Xie, Xianghong; Wang, Rong; Zhang, Xixi; Ren, Yarong; Du, Ting; Ni, Yongsheng; Yan, Huiling; Zhang, Liang; Sun, Jing; Zhang, Wentao; Wang, Jianlong
	2021
发表期刊	APPLIED CATALYSIS B-ENVIRONMENTAL
卷号	295
摘要	Although the single-modal antibacterial technology has received widespread attention, it has limitations because of challenges associated with the complete eradication of bacteria. Herein, we present a synergistic antibacterial strategy based on copper peroxide loaded-tungsten disulfide nanoflowers (CP@WS2 NFs). In this system, copper peroxide can self-supply H2O2 to activate the Fenton reaction, which causes the destruction of some bacteria under acidic condition. Under near-infrared laser irradiation, WS2 NFs transform light-to-localized heat to eliminate the remaining bacteria. The system can cause serious leakage of cell components, reduce the amount of adenosine triphosphate and destroy the bacterial membrane. In vitro experiments indicated a predominant synergistic antibacterial effect on Escherichia coli and Staphylococcus aureus. In vivo experiments of wound healing confirmed that the system can enhance bacterial elimination, concurrently promoting wound healing with high biocompatibility. In addition, our study reveals a promising dimension for the rational design of a synergistic antibacterial system.
关键词	Fenton reaction Photothermal therapy Wound anti-infective therapy pH responsive
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/60692
专题	中国科学院西北高原生物研究所
推荐引用方式 GB/T 7714	Xie, Xianghong,Wang, Rong,Zhang, Xixi,et al. A photothermal and self-induced Fenton dual-modal antibacterial platform for synergistic enhanced bacterial elimination[J]. APPLIED CATALYSIS B-ENVIRONMENTAL,2021,295.
APA	Xie, Xianghong.,Wang, Rong.,Zhang, Xixi.,Ren, Yarong.,Du, Ting.,...&Wang, Jianlong.(2021).A photothermal and self-induced Fenton dual-modal antibacterial platform for synergistic enhanced bacterial elimination.APPLIED CATALYSIS B-ENVIRONMENTAL,295.
MLA	Xie, Xianghong,et al."A photothermal and self-induced Fenton dual-modal antibacterial platform for synergistic enhanced bacterial elimination".APPLIED CATALYSIS B-ENVIRONMENTAL 295(2021).