Genetic variation in bitter taste receptor genes influences the foraging behavior of plateau zokor (Eospalax baileyi)

doi:10.1002/ece3.2041

NWIPB OpenIR

	Genetic variation in bitter taste receptor genes influences the foraging behavior of plateau zokor (Eospalax baileyi)
	Zhao, Fang 1,2; Zhang, Tongzuo 1; Xie, Jiuxiang 3; Zhang, Shoudong 1; Nevo, Eviatar 4; Su, Jianping 1; Lin, Gonghua 1
	2016-04-01
发表期刊	ECOLOGY AND EVOLUTION
卷号	6 期号:8 页码:2359-2367
文章类型	Article
摘要	The ability to detect bitter tastes is important for animals; it can help them to avoid ingesting harmful substances. Bitter taste perception is mainly mediated by bitter taste receptor proteins, which are encoded by members of the Tas2r gene family and vary with the dietary preference of a specific species. Although individuals with different genotypes differ in bitterness recognition capability, little is known about the relationship between genetic variation and food selection tendencies at the intraspecific level. In this study, we examined the relationship between genotypes and diet in plateau zokor (Eospalax baileyi), a subterranean rodent endemic to the Qinghai-Tibet Plateau that caches food for the winter. We assayed the composition and taste profile of each plant contained in temporary caches and vicinity quadrats, which were representative of selected and available food, respectively. Bitter plant selection indices (E-bitter) were estimated. We also sequenced 26 candidate Tas2r genes from zokors and determined their relationships with the Ebitter of their caches. We identified four key results: (1) zokors varied considerably in both bitter food preference and Tas2r sequences; (2) five genes (zTas2r115, zTas2r119, zTas2r126, zTas2r134, and zTas2r136) exhibited allelic variation that was significantly associated with E-bitter; (3) synonymous SNPs, nonsynonymous SNPs, and pseudogenization are involved in the genotype-phenotype relationship; (4) the minor genotypes of zTas2r115, zTas2r134, and zTas2r136 and the major genotypes of zTas2r119 and zTas2r126 cached more bitter plants. Our results link Tas2r variation with food selection behavior at the population level for the first time.
关键词	Bitter Taste Food Selection Single-nucleotide Polymorphism Subterranean Rodent
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
DOI	10.1002/ece3.2041
关键词[WOS]	DIVERSIFICATION ; INTEGRATION ; EVOLUTION ; CACHES ; MOUSE
收录类别	SCI
语种	英语
项目资助者	National Natural Science Foundation of China(31372197) ; Youth Innovation Promotion Association of Chinese Academy of Sciences(2015352) ; Key Technologies Research and Development Program of Qinghai Province(2014-NS-113)
WOS研究方向	Environmental Sciences & Ecology
WOS类目	Ecology
WOS记录号	WOS:000374568300010
引用统计	被引频次：2[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://210.75.249.4/handle/363003/5752
专题	中国科学院西北高原生物研究所
作者单位	1.Chinese Acad Sci, Northwest Inst Plateau Biol, Key Lab Adaptat & Evolut Plateau Biota, Xining 810001, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Qinghai Univ, Dept Grass Sci, Xining 810016, Qinghai, Peoples R China 4.Univ Haifa, Inst Evolut, IL-3498838 Haifa, Israel
推荐引用方式 GB/T 7714	Zhao, Fang,Zhang, Tongzuo,Xie, Jiuxiang,et al. Genetic variation in bitter taste receptor genes influences the foraging behavior of plateau zokor (Eospalax baileyi)[J]. ECOLOGY AND EVOLUTION,2016,6(8):2359-2367.
APA	Zhao, Fang.,Zhang, Tongzuo.,Xie, Jiuxiang.,Zhang, Shoudong.,Nevo, Eviatar.,...&Lin, Gonghua.(2016).Genetic variation in bitter taste receptor genes influences the foraging behavior of plateau zokor (Eospalax baileyi).ECOLOGY AND EVOLUTION,6(8),2359-2367.
MLA	Zhao, Fang,et al."Genetic variation in bitter taste receptor genes influences the foraging behavior of plateau zokor (Eospalax baileyi)".ECOLOGY AND EVOLUTION 6.8(2016):2359-2367.