Knowledge Management System of Northwest Institute of Plateau Biology, CAS
Computational probing protein-protein interactions targeting small molecules | |
Wang, Yong-Cui ; Chen, Shi-Long ; Deng, Nai-Yang ; Wang, Yong | |
2016-01-15 | |
发表期刊 | BIOINFORMATICS |
摘要 | Motivation: With the booming of interactome studies, a lot of interactions can be measured in a high throughput way and large scale datasets are available. It is becoming apparent that many different types of interactions can be potential drug targets. Compared with inhibition of a single protein, inhibition of protein-protein interaction (PPI) is promising to improve the specificity with fewer adverse side-effects. Also it greatly broadens the drug target search space, which makes the drug target discovery difficult. Computational methods are highly desired to efficiently provide candidates for further experiments and hold the promise to greatly accelerate the discovery of novel drug targets. |
文献类型 | 期刊论文 |
条目标识符 | http://210.75.249.4/handle/363003/22762 |
专题 | 中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Wang, Yong-Cui,Chen, Shi-Long,Deng, Nai-Yang,et al. Computational probing protein-protein interactions targeting small molecules[J]. BIOINFORMATICS,2016. |
APA | Wang, Yong-Cui,Chen, Shi-Long,Deng, Nai-Yang,&Wang, Yong.(2016).Computational probing protein-protein interactions targeting small molecules.BIOINFORMATICS. |
MLA | Wang, Yong-Cui,et al."Computational probing protein-protein interactions targeting small molecules".BIOINFORMATICS (2016). |
条目包含的文件 | 条目无相关文件。 |
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